室间隔穿孔是急性心肌梗死的急性并发症之一，虽然发病率很低，但是内科保守治疗效果很差，识别心肌梗死后并发穿孔的危险因素，及时确诊室间隔穿孔，适时通过外科手术或介入封堵的方法修补室间隔，是改变此类危重症患者预后的关键。
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